A 35-year-old woman with an intrasellar and suprasellar lesion.

摘要

A 35-year-old woman was admitted to our hospital with symptoms and signs of acromegaly that started 1 year earlier. Physical examination detected clubbing of her fingers, enlargement of her jaws, a carpal tunnel syndrome along with joint and neck pain. Laboratory findings showed hypothyroidism, secondary hypogonadism, diabetes mellitus and anemia. Cranial MRI revealed an intrasellar and suprasellar mass lesion with radiological signs of a chiasma syndrome. She was treated with a somatostatin therapy. Although the clinical symptoms improved over the next 3 months, Insulin like Growth Factor-1 levels (a marker for acromegaly) continued to be at pathological levels. The patient therefore underwent a transphe-noidal resection of the intrasellar mass.