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44-YEAR-OLD MAIM WITH ABNORMAL GAIT

机译:步态异常的44岁MAIM

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A 44-year-old man was hospitalized with an acute onset of giddiness, drunken gait and tendency to fall. He was apparently well until 1 week prior to presentation. He experienced these symptoms after drinking heavily at a party. There was no history of trauma, headache, vomiting or seizures.On neurological examination, there was no motor or sensory deficit. Finger-to-nose testing revealed mildly abnormal coordination. The patient tended to sway and fall ^rdeways on heel-to-toe walking. Romberg's test was mildly positive. Meningeal signs were absent.Computed tomography (CT) scan revealed a large hyper-dense calcified lesion in the fourth ventricle. Magnetic resonance imaging scans showed a fourth ventricular space-occupying lesion with mild hydrocephalus. Craniectomy with endoscopic fourth ventriculostomy was performed. A reddish brown tumor mass wasencountered measuring 30 mm x 20 mm attached to the floor of the fourth ventricle. The tumor was almost entirely resected.Histopathological examination revealed a moderately cellular tumor with large areas of calcification (Figures 1 and 2). The tumor cells were arranged in groups and cords as well as showing papillary formation in many areas. The tumor cells were generally large and contained brightly eosinophilic granular cytoplasm with central nuclei (Figure 3). There was only mild nuclear pleomor-phism and mitoses were rare.
机译:一名44岁的男子因头晕,醉酒的步态和跌倒的急性发作入院。演讲之前的1周之前,他的状况似乎一直很好。在聚会上大量喝酒后,他经历了这些症状。无外伤,头痛,呕吐或癫痫发作史,神经系统检查无运动或感觉障碍。指鼻测试显示轻度异常协调。病人在脚跟到脚尖走路时倾向于摇摆和倒下。 Romberg的检验呈轻微阳性。没有脑膜体征。计算机断层扫描(CT)扫描显示第四脑室有大的高密度钙化病变。磁共振成像扫描显示有轻度脑积水的第四个心室占位性病变。行内窥镜颅内切除第四脑室造口术。遇到附着在第四脑室底部的棕褐色肿瘤块,大小为30 mm x 20 mm。肿瘤几乎全部切除。组织病理学检查显示为中等细胞瘤,钙化面积较大(图1和2)。肿瘤细胞按组和脐带排列,并在许多区域显示出乳头状形成。肿瘤细胞通常很大,并含有明亮的嗜酸性粒状细胞质和中心核(图3)。仅有轻度的核多态性,有丝分裂很少见。

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