GRAS flavoring substances 20 Review

摘要

In 1958, Congress enacted the Food Additives Amendment (FAA) to the Federal Food, Drug, and Cosmetics Act amid growing concern over the safety of substances added to foods. The FAA set forth standards and guidelines by which the safety of food additives must be established before they can be added to foods (FAA, 1958). The FAA contained an exclusion provided by Congress for substances "generally recognized, by experts qualified by scientific training and experience to evaluate its safety, as having been adequately shown through scientific procedures.., to be safe under the conditions of intended use." Based on this, substances "generally recognized as safe" (GRAS) are not considered to be food additives, and are excluded from mandatory premarket approval by the Food and Drug Administration (FDA). However, GRAS substances must meet strict criteria specified by Congress (Degnan, 1991).