A modified pulse sequence forin vivodiffusion imaging with reduced motion artifacts

摘要

AbstractA modified spin‐echo diffusion imaging pulse sequence incorporating bipolar gradients that is less sensitive to macroscopic motion‐induced artifacts is presented. Expressions for apparent diffusion coefficient in the presence of microcirculation and macroscopic motions and contrast‐to‐noise ratio in the diffusion map are derived. Diffusion coefficients of liquid phantoms have been measured using a 1.5‐T GE Signa system. Experiments performed to demonstrate the immunity to motion‐induced errors are reported. Brain images from human volunteer have also been included to show the potential clinical application of the proposed pulse sequence. © 1991 Academi