Abstract.To study survival and function of leukocyte‐poor platelet concentrates (lp‐PC) prepared from buffy coats, random platelet transfusions requested for thrombocytopenic patients were evaluated. The lp‐PC issued were stored at 22°C for either 1, 3 or 5 days before transfusion. From 31 transfusions, posttransfusion corrected count increments (CCI), corrected for body surface (m2) and divided by number of platelets transfused (1011), were calculated. The mean ±SEM of the 1‐, 24‐and 48‐hour CCI was 12.2 ± 0.45, 11.2 ± 0.51 and 8.8 ± 0.58, respectively. No significant differences in CCI 24 h after transfusion were observed for lp‐PC stored for 1, 3 or 5 days. Hemostatic activity was observed in all 9 evaluable patients. It is concluded that platelets from lp‐PC survive well in patients, regardless of storage for 1, 3 or 5 days and that the platelets are hemostatically acti
展开▼