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首页> 外文期刊>Indian journal of physiology and pharmacology >MATERNAL AND NEONATAL FACTORS AFFECTING PHYSIOLOGICAL JAUNDICE IN WESTERN U.P.
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MATERNAL AND NEONATAL FACTORS AFFECTING PHYSIOLOGICAL JAUNDICE IN WESTERN U.P.

机译:影响西美国西部生理黄疸的主要因素和新生儿因素

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摘要

Several maternal and fetal factors are responsible for neonatal jaundice, which is a common observation in large number of newborns. However, role of these factors in causation of this condition is not well established. Fifty pregnant mothers and their fifty two newborns were studied in the present study. Mothers with complicated pregnancy or septicemia at the time of delivery were excluded. In addition newborns with congenital or chromosomal abnormalities were excluded. Serum concentrations of bilirubin of all neonates were measured on days 1, 3 and 5. It was found to be lower on day 1, with a peak at day 3. The area under serum bilirubin level-time curve (AUC) for each neonate was also calculated. Fetal sex and birth weight were not found to significantly affect the neonatal hyperbilirubinemia. Newborn of bipara mothers were found to have significantly lower (P<0.05) serum bilirubin level on day 1 as compared to primipara mothers only but higher (P<0.05) on day 3 as compared to either primi or multipara mothers. Yet, AUC of serum bilirubin curve was significantly higher (P<0.05) in newborns of bipara mothers than others. Significantly (P<0.05) higher serum bilirubin on day 1 was also observed in preterm neonates than full term ones. However, maternal haemoglobin and mode of delivery were not shown to affect the neonatal bilirubin levels in these newborns.
机译:新生儿黄疸是由多种母体和胎儿因素引起的,这在大量新生儿中很常见。但是,这些因素在导致这种情况的作用中的作用尚不明确。在本研究中研究了五十名怀孕的母亲及其五十二个新生儿。分娩时有复杂妊娠或败血症的母亲被排除在外。此外,排除了先天性或染色体异常的新生儿。在第1、3和5天测量所有新生儿的血清胆红素浓度。发现在第1天血胆红素浓度降低,在第3天达到峰值。每个新生儿的血清胆红素水平-时间曲线(AUC)下面积为也算了。未发现胎儿性别和出生体重显着影响新生儿高胆红素血症。发现双亲母亲的新生儿在第1天的血清胆红素水平仅比初产妇高(P <0.05),但在第3天与初产妇或多产妇相比则更高(P <0.05)。然而,双亲母亲的新生儿血清胆红素曲线的AUC明显高于其他人(P <0.05)。早产儿在第一天的血清胆红素也明显高于足月儿(P <0.05)。但是,未显示母亲的血红蛋白和分娩方式会影响这些新生儿的新生儿胆红素水平。

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