SummaryA spontaneous discharge‐like wave in widespread cortical areas was induced by a strong click stimulation under very deep pheno‐barbital anesthesia in cats.This phenomenon was facilitated by the destruction of the midbrain reticular formation and abolished after the bilateral destruction of the classic acoustic pathway up to the medial geniculate body.We believe that this phenomenon was a kind of arousal reaction and the mechanism by which this phenomenon produced was independent ofMagoun'sactivating system in the lower brain s
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