Aldosterone Antagonists or Renin-Guided Therapy for Treatment-Resistant Hypertension: A Comparative Effectiveness Pilot Study in Primary Care

摘要

Uncontrolled treatment-resistant hypertension (TRH), i.e., blood pressure (BP, mm Hg) a parts per thousand yen140/a parts per thousand yen90mm Hg in and out of office on a parts per thousand yen3 different BP medications at optimal doses, is common and has a poor prognosis. Aldosterone antagonist (AA) and renin-guided therapy (RGT) are effective strategies for improving BP control in TRH but have not been compared.