Synthesis of N_8-macrocyclic ligands by polyphosphoric acid-catalysed condensation of trimethoprim with amino acids

M Amaladasan; A PAULRAJ; K S Arulsamy

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Synthesis of N_8-macrocyclic ligands by polyphosphoric acid-catalysed condensation of trimethoprim with amino acids

机译：多磷酸催化甲氧苄啶与氨基酸的缩合反应合成N_8-大环配体

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摘要

Trimethoprim [2,4-diamino-5-(3min,4min,5min-triemthoxybenzyl) pyrimidine] reacts with amino acids to give colourless N_8-macrocyclic compounds by the polyphosphoric acid-catalysed condensation.

机译：甲氧苄啶[2,4-二氨基-5-（3min，4min，5min-三乙氧基苄基）嘧啶]与氨基酸反应，通过多磷酸催化的缩合反应生成无色的N_8-大环化合物。

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《Indian Journal of Chemistry, Section B. Organic Including Medicinal》 |1999年第11期|共2页
作者
M Amaladasan; A PAULRAJ; K S Arulsamy;
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中图分类化学;化学工业;
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1. Synthesis of N_8-macrocyclic ligands by polyphosphoric acid-catalysed condensation of trimethoprim with amino acids [J] . M Amaladasan, A PAULRAJ, K S Arulsamy Indian Journal of Chemistry, Section B. Organic Including Medicinal . 1999,第11期

机译：多磷酸催化甲氧苄啶与氨基酸的缩合反应合成N_8-大环配体
2. Synthesis of novel indole-based ring systems by acid-catalysed condensation from alpha-amino aldehydes and L-Trp-OMe [J] . Gomez-Monterrey IM, Campiglia P, Bertamino A, European journal of organic chemistry . 2008,第11期

机译：由α-氨基醛和L-Trp-OMe进行酸催化缩合合成新型基于吲哚的环系统
3. One-step synthesis of pyrido[2,3-d]pyrimidines, amides, and benzoxazolylethylpyrimidine by condensation of substituted 3-(2-phenylpyrimidin-5-yl)propanoic acids with aromatic amines in polyphosphoric acid [J] . Harutyunyan A. A., Panosyan H. A., Chishmarityan S. G., Russian Journal of Organic Chemistry . 2015,第3期

机译：通过取代的3-（2-苯基嘧啶-5-基）丙酸与芳香胺在多磷酸中的缩合一步合成吡啶并[2,3-d]嘧啶，酰胺和苯并恶唑基乙基嘧啶
4. Synthesis and Application of Chiral α-Amino Acids by Kinetic Resolution of Urethane-Protected α-Amino Acid N-Carboxyanhydrides with Modified Cinchona Alkaloid Catalysts [C] . Jianfeng Hang, Yutaka Ishii, Yoshiro Furukawa, Asymmetric synthesis and application of α-amino acids . 2007

机译：改性金鸡纳生物碱催化剂动力学拆分氨基甲酸酯保护的α-氨基酸N-羧酸酐合成手性α-氨基酸及其应用
5. Asymmetric synthesis of conformationally and topographically constrained amino acids as peptidomimetics: An approach to design and synthesis of opioid receptor selective ligands. [D] . Xiong, Chiyi. 2003

机译：构象和地形约束氨基酸作为拟肽的不对称合成：一种设计和合成阿片受体选择性配体的方法。
6. Synthesis Characterization and Antibacterial Activities of Novel Sulfonamides Derived through Condensation of Amino Group Containing Drugs Amino Acids and Their Analogs [O] . Muhammad Abdul Qadir, Mahmood Ahmed, Muhammad Iqbal -1

机译：含氨基的药物氨基酸及其类似物缩合衍生的新型磺酰胺的合成表征和抗菌活性
7. Synthesis of Phenylhydrocoumarins by using Polyphosphoric Acid as a Condensation Reagent [O] . Noboru HASEBE 1962

机译：用多磷酸作为缩合试剂合成苯基氢脲草林

Synthesis of N_8-macrocyclic ligands by polyphosphoric acid-catalysed condensation of trimethoprim with amino acids

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