An efficient synthesis of 2-aminobenzochromene derivatives catalysed by tetrabutylammoniumbromide (TBABr) under microwave irradiation in aqueous medium

摘要

TBABr efficiently catalyzes the three-component coupling of substituted aldehyde, alpha-naphthol or beta-naphthol and malononitrile to afford the corresponding 2-aminobenzochromene, the new protocol under microwave irradiation works in the absence of organic solvent, the yields are high and the reactions go to completion within 2-3 min.