Synthesis of pyrazolines promoted by Amberlyst-15 catalyst

摘要

The condensation of a series of aromatic ketones with aromatic aldehydes under aldol conditions affords l-aryl-3-(substituted-phenyl/phenyl furanyl/thienyl)-2-propen-l-ones 1.The resulting propenones undergo facile and clean cyclization with hydrazine and substituted hydrazine derivatives to yield 3-aryl-5-(substitutedphenyl/phenylfuranyl/thienyl)-2-pyrazolines 2.This reaction is carried out in the presence of Amberlyst-15 catalyst to afford the above pyrazolines 2 in considerably good yield.All the synthesized compounds have been characterized by spectral studies.