One-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones catalyzed by acidic ionic liquid

摘要

3,4-Dihydropyrimidin-2(1H)-ones have been synthesized via one-pot reaction of aromatic aldehydes,ethyl acetoacetate and urea or thiourea catalyzed by room temperature ionic liquid [hmim]HSO4.It has been observed that the proposed method is fast,efficient and environmentally benign.The reaction time is 15 ~ 55 min with the yields between 82 ~ 97 %.