Synthesis of biologically active 4-coumarin-6-yl(amino)-5-coumarin-3-yl-3-phenyl-1,2,4-oxadiazolines

摘要

Reaction of Schiff bases 3 and hydrazones 6 with benzhydroxamoyl chloride respectively afforded the corressponding 4-coumarin-6-yl(amino)-5-coumarin-3-yl-3-phenyl-1,2,4-oxadiazolines 4 and 7.The structures of all the synthesized compounds have been confirmed on the basis of spectral and analytical data.The above compounds have been screened for their antibacterial activity.