Synthesis of 3-(6-aryl-pyridin-2-yl)- and 8-(6-aryl-pyridin-2-yl) coumarins

Brahmbhatt DI; Gajera JM; Pandya VP; Patel MA

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Synthesis of 3-(6-aryl-pyridin-2-yl)- and 8-(6-aryl-pyridin-2-yl) coumarins

机译：3-（6-芳基-吡啶-2-基）和8-（6-芳基-吡啶-2-基）香豆素的合成

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摘要

Mannich bases of 3-acetyl coumarin 1 and 4-rnethyl-7-methoxy-8-acetyl coumarin 4 on reaction with substituted phenacyl bromide pyridinium salts 2a-f in the presence of ammonium acetate in refluxing acetic acid afford the title 3-(6-aryl-pyridin-2-yl)- and 8-(6-aryl-pyridin-2-yl) coumarins (3a-f and 5a-f) in moderate to good yields.

机译：3-乙酸香豆素1和4-甲基乙基-7-甲氧基-8-乙酰香豆素4的曼尼希碱在乙酸铵存在下于回流的乙酸中与取代的苯甲酰溴吡啶鎓盐2a-f反应得到标题3-（6 -芳基-吡啶-2-基）和8-（6-芳基-2-基）香豆素（3a-f和5a-f），产率中等至良好。

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《Indian Journal of Chemistry, Section B. Organic Including Medicinal》 |2007年第5期|共3页
作者
Brahmbhatt DI; Gajera JM; Pandya VP; Patel MA;
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原文格式 PDF
正文语种 eng
中图分类化学;
关键词
coumarins; pyridinium salts; Mannich bases; COUMARINS;

机译：香豆素;吡啶盐;曼尼希碱;库马林斯;

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专利

1. Synthesis of 3-(6-aryl-pyridin-2-yl)- and 8-(6-aryl-pyridin-2-yl) coumarins [J] . Brahmbhatt DI, Gajera JM, Pandya VP, Indian Journal of Chemistry, Section B. Organic Including Medicinal . 2007,第5期

机译：3-（6-芳基-吡啶-2-基）和8-（6-芳基-吡啶-2-基）香豆素的合成
2. Synthesis and antimicrobial screening of some 3 -[4-(3-aryl-1-phenyl- 1H-pyrazol-4-yl)-6-aryl-pyridin-2-yl] and 4-methyl-3-phenyl-6-[4-(3-aryl-1-phenyl-1H-pyrazol-4-yl)-6-aryl-pyridin-2-yl] coumarins [J] . D I Brahmbhalt, Ankit R Kaneria, Anil K Patel Indian Journal of Chemistry, Section B. Organic Including Medicinal . 2010,第7期

机译：某些3- [4-（3-芳基-1-苯基-1H-吡唑-4-基）-6-芳基吡啶-2-基]和4-甲基-3-苯基-6-的合成及抗菌筛选[4-（3-芳基-1-苯基-1H-吡唑-4-基）-6-芳基吡啶-2-基]香豆素
3. Synthesis of some new 3-(6-arylpyridin-2-yl)- and 8-(6-arylpyridin-2-yl)coumarins [J] . D I Brahmbhatt, Urvish R Pandya Indian Journal of Chemistry, Section B. Organic Including Medicinal . 2001,第5期

机译：一些新的3-（6-芳基吡啶-2-基）-和8-（6-芳基吡啶-2-基）香豆素的合成
4. Synthesis and antibacterial activity test of 3-(3-(4-hydroxy-3-methylphenyl)akriIoil)coumarin compounds [C] . Ismiyarto, Fida Hidayatul Rafiah, Novianita Rizky Joint Conference on Chemistry . 2019

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6. Uses of 3-(2-Bromoacetyl)-2H-chromen-2-one in the Synthesis of Heterocyclic Compounds Incorporating Coumarin: Synthesis Characterization and Cytotoxicity [O] . Rafat M. Mohareb, Nadia Y. MegallyAbdo 2015

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7. A novel method for the synthesis of coumarin laser dyes derived from 3-(1H-benzoimidazol-2-yl) coumarin-2-one under microwave irradiation [O] . Ghasem Bakhtiari, Shahram Moradi, Saeed Soltanali 2014

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Synthesis of 3-(6-aryl-pyridin-2-yl)- and 8-(6-aryl-pyridin-2-yl) coumarins

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