Synthesen von Siebenerringsystemen aus substituierten Isothiocyanaten und Hydrazinen

摘要

The β-isothiocyanato-ketone 1 reacts with substituted hydrazines (2) in alkaline solution to form 2-alkyl-5,6-dihydro-(2H)-1,2,4-triazepine-3(4H)-thiones (3); the intermediate thiosemicarbazide derivatives (6), formed by addition of the hydrazine derivatives to the isothiocyanate group, could be isolated. CH3I and BrCH2COOC2H5alkylate3at sulfur, and the fusedring compounds14and16were isolated