Bone marrow trephine biopsy findings in B acute lymphoblastic leukaemia of early precursor (Pro-B) subtype.

摘要

The blasts in the peripheral blood were large with moderate amounts of pale blue agranular cytoplasm. The nuclear membrane was irregular, and the nuclei showed relatively fine chromatin, and a single prominent nucleolus or rarely two nucleoli (Fig. 1a-c). Bone marrow aspirate identified similar cells, and they accounted for >70% of the marrow cells (Fig. 1d,e). Flow cytometry showed expression of CD34, TdT, HLADR, CD123, CD38, and CD79a (39% cells) in the blasts, but the cells were negative CD10, CD19, CD20, cCD22, clgM, CD1a, CD2, CD3, CD7, CD4, CD8, CD5, cCD3, CD56, CD13, CD14, myeloperoxidase, CD15, lysozyme, CD11b, CD33, CD117, and CD64.