Synthesis of iV-Substituted 1,2,4-Triazoles. A Review

摘要

Although the 1,2,4-triazole fragment is unknown in any natural product, 1,2,4-triazoles show high levels of biological activity as herbicides and fungicides. 1,2,4-Triazoles such as propiconazol (Figure 1) are highly efficient fungicides and are in use as broad-spectrum fungicides in agriculture. The biological effect of 1,2,4-triazole fungicides originates from the inhibition of the biosynthesis of ergosterol in fungi.