A convenient method for the oxidation of Hantzsch 1,4-dihydropyridines with N-bromo succinimide

R Nagarajan; J C A Anthonyraj; D Muralidharan; C Saikumar; P T Perumal

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A convenient method for the oxidation of Hantzsch 1,4-dihydropyridines with N-bromo succinimide

机译：N-溴琥珀酰亚胺氧化Hantzsch 1,4-二氢吡啶的简便方法

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摘要

A convenient and mild method for the conversion of Hantzsch 1,4-dihydropyridines to pyridines using N-bromo succinimide at room temperature in excellent yields has been described.Dihydropyridines are of utmost importance in biological systems as a class of useful drugs particularly as anti-oxidants.

机译：已经描述了一种在室温下使用N-溴代琥珀酰亚胺以高收率将Hantzsch 1,4-二氢吡啶转化为吡啶的便捷，温和的方法。二氢吡啶作为一类有用的药物在生物系统中至关重要，特别是作为抗氧化剂。

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《Indian Journal of Chemistry, Section B. Organic Including Medicinal》 |2006年第3期|共3页
作者
R Nagarajan; J C A Anthonyraj; D Muralidharan; C Saikumar; P T Perumal;
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正文语种 eng
中图分类化学;
关键词
Hantzsch 1; 4-dihydropyridines; pyridines; N-bromo succinimide;

机译：Hantzsch 1;4-二氢吡啶;吡啶;N-溴琥珀酰亚胺;

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1. A convenient method for the oxidation of Hantzsch 1,4-dihydropyridines with N-bromo succinimide [J] . R Nagarajan, J C A Anthonyraj, D Muralidharan, Indian Journal of Chemistry, Section B. Organic Including Medicinal . 2006,第3期

机译：N-溴琥珀酰亚胺氧化Hantzsch 1,4-二氢吡啶的简便方法
2. A convenient and efficient protocol for oxidative aromatization of Hantzsch 1,4-dihydropyridines using benzyltriphenylphosphonium peroxymonosulfate under almost neutral reaction conditions. [J] . Adibi H, Hajipour AR Bioorganic and Medicinal Chemistry Letters . 2007,第4期

机译：在几乎中性的反应条件下，使用苄基三苯基phosph过氧单硫酸盐对Hantzsch 1,4-二氢吡啶进行氧化芳构化的便捷高效方法。
3. 3-Carboxypyridinium chlorochromate (CPCC): an inexpensive and convenient reagent for efficient oxidation of hantzsch 1,4-dihydropyridines [J] . Iraj Mohammadpoor-Baltork, Majid M.M.Sadeghi, Hamid Reza Memarian, Journal of Chemical Research. Synopses . 2001,第1期

机译：3-羧基吡啶鎓氯铬酸盐（CPCC）：一种廉价，方便的试剂，可有效氧化汉茨1,4-二氢吡啶
4. A Detailed Investigation on the Oxidation Mechanism of Hantzsch 1,4-Dihydropyridines by Ethyl α-Cyanocinnamates and Benzylidenemalononitriles [C] . Xiao-Qing Zhu International symposium for Chinese organic chemists . 2000

机译：乙基α-氰基氨基酸乙基α-氰基丙烯酸盐和苄基甲醛氧化物1,4-二氢吡啶氧化机理的详细研究
5. Investigating The Anti-Cancer Properties of Novel Hybrid 1,4-Dihydropyridine Derivatives in U-87mg Glioblastoma Cell Line [D] . Hunyenyiwa, Tendai 2019

机译：在U-87mg胶质母细胞瘤细胞系中研究新型杂种1,4-二氢吡啶衍生物的抗癌特性
6. One-pot multicomponent green Hantzsch synthesis of 12-dihydropyridine derivatives with antiproliferative activity [O] . Giovanna Bosica, Kaylie Demanuele, José M Padrón, 2020

机译：抗增殖活性12-二氢吡啶衍生物的单壶多组分绿色汉庭合成
7. Oxidation of Hantzsch 1,4-Dihydropyridines Using Supported Nitric Acid on Silica Gel and Poly Vinyl Pyrrolidone (PVP) under Mild and Heterogeneous Conditions [O] . 2009

机译：在轻度和异质条件下，在硅胶上使用负载硝酸和聚乙烯基吡咯烷酮（PVP）在硅胶和聚乙烯基吡咯烷酮（PVP）下氧化氧化术1,4-二氢吡啶

A convenient method for the oxidation of Hantzsch 1,4-dihydropyridines with N-bromo succinimide

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