Synthesis of methyl-5-[2-arylamino-4-(3-oxo-1,4-benzoxazin-6-yl)thiazole acetates and 7H-[3-aryl-6-(3-oxo-1,4-benzoxazin-6-yl)-s-triazolo[3,4-b][1,3,4]thiadiazin-7-yl]acetates as possible COX-2-inhibitors

G Jagath Reddy; K Srinivasa Rao

首页> 外文期刊>Indian Journal of Chemistry, Section B. Organic Including Medicinal >Synthesis of methyl-5-[2-arylamino-4-(3-oxo-1,4-benzoxazin-6-yl)thiazole acetates and 7H-[3-aryl-6-(3-oxo-1,4-benzoxazin-6-yl)-s-triazolo[3,4-b][1,3,4]thiadiazin-7-yl]acetates as possible COX-2-inhibitors

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Synthesis of methyl-5-[2-arylamino-4-(3-oxo-1,4-benzoxazin-6-yl)thiazole acetates and 7H-[3-aryl-6-(3-oxo-1,4-benzoxazin-6-yl)-s-triazolo[3,4-b][1,3,4]thiadiazin-7-yl]acetates as possible COX-2-inhibitors

机译：甲基-5- [2-芳基氨基-4-（3-氧代-1,4-苯并恶嗪-6-基）噻唑乙酸酯和7H- [3-芳基-6-（3-氧代-1,4-苯并恶嗪）的合成-6-yl）-s-三唑并[3,4-b] [1,3,4]噻二嗪-7-基]乙酸盐可能是COX-2-抑制剂

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A series of methyl 5-[2-arylamino-4-(3-oxo-[1,4]benzoxazin-6-yl)thiazoleacetates 5a-h and 7H-[3-aryl-6-(3-oxo-[1,4]-benzox-azin-6-yl)-s-triazolo[3,4-b][1,3,4]thiadiazin-7-yl]acetates 6a-e have been synthesized and tested for their COX-2 inhibitor activity.

机译：一系列5- [2-芳基氨基-4-（3-氧代-[1,4]苯并恶嗪-6-基）噻唑乙酸甲酯5a-h和7H- [3-芳基-6-（3-氧代-[1合成了4,4]-苯并恶嗪-6-基）-三唑[3,4-b] [1,3,4]噻二嗪-7-基]乙酸酯6a-e，并测试了其COX-2抑制剂活性。

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《Indian Journal of Chemistry, Section B. Organic Including Medicinal》 |2006年第9期|共4页
作者
G Jagath Reddy; K Srinivasa Rao;
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正文语种 eng
中图分类化学;
关键词
Benzoxazin; v-bromobenzoxazinyl butanoate; thiazolyl-benzoxazinyl acetates; triazolothiadiazinyl benzox-azinyl acetate; COX-2 inhibitors.;

机译：苯并恶嗪;v-溴苯并恶嗪基丁酸酯;噻唑基-苯并恶嗪基乙酸酯;三唑并噻二嗪基苯并恶唑啉基乙酸酯;COX-2抑制剂。;

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1. Synthesis of methyl-5-[2-arylamino-4-(3-oxo-1,4-benzoxazin-6-yl)thiazole acetates and 7H-[3-aryl-6-(3-oxo-1,4-benzoxazin-6-yl)-s-triazolo[3,4-b][1,3,4]thiadiazin-7-yl]acetates as possible COX-2-inhibitors [J] . G Jagath Reddy, K Srinivasa Rao Indian Journal of Chemistry, Section B. Organic Including Medicinal . 2006,第9期

机译：甲基-5- [2-芳基氨基-4-（3-氧代-1,4-苯并恶嗪-6-基）噻唑乙酸酯和7H- [3-芳基-6-（3-氧代-1,4-苯并恶嗪）的合成-6-yl）-s-三唑并[3,4-b] [1,3,4]噻二嗪-7-基]乙酸盐可能是COX-2-抑制剂
2. Synthesis of some new 1-(3-oxo-1,4-benzoxazin-6-yl) ethanone (4-aryl-1,3-thiazol-2-yl) hydrazones [J] . Reddy GJ, Rao KS, Khalilullah M, Heterocyclic communications . 2006,第6期

机译：一些新的1-（3-氧代-1,4-苯并恶嗪-6-基）乙酮（4-芳基-1,3-噻唑-2-基）的合成
3. Synthesis of some new 6-aryl-2-(3-oxo-1,4-benzoxazin-6-yl)pyridines [J] . Reddy PSN, Reddy P, Reddy GJ, Heterocyclic communications . 2005,第2期

机译：一些新的6-芳基-2-（3-氧代-1,4-苯并恶嗪-6-基）吡啶的合成

Synthesis of methyl-5-[2-arylamino-4-(3-oxo-1,4-benzoxazin-6-yl)thiazole acetates and 7H-[3-aryl-6-(3-oxo-1,4-benzoxazin-6-yl)-s-triazolo[3,4-b][1,3,4]thiadiazin-7-yl]acetates as possible COX-2-inhibitors

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