Synthesis of benzo[b]furan Mannich bases under solventless,PTSA/FTC catalytic conditions assisted by microwave irradiation

摘要

Condensation of 2-aroyl-6-hydroxy-3-methyl-5-acetyl-benzo-[b]furan with different amines and paraformaldehyde in the presence of p-toluene sulfonic acid(PTSA)or PTC [tetra butyl ammonium sulphate] leads to the synthesis of benzo[b]furan Mannich bases by a solventless PTSA/PTC catalytic reaction under microwave irradiation.