Combinatorial chemistry:A novel method in drug discovery and its application

摘要

Combinatorial chemistry is a new technique developed in pharmaceutical industry,which involves synthesis of compounds in mass instead of a single compound,which are screened as a whole mixture for particular biological activity.Because of the rapid synthesis of compounds,this method saves the time and cost associated with the drug discovery.This brief review article includes combinatorial strategies,screening methods and encoding technologies and some of the applications in drug discovery.