Synthesis of new 1-hydroxyindole derivatives

摘要

The reactivity of the amino and hydroxy groups of the hydroxyindole derivatives has been investigated. A one-pot synthetic approach to the novel ethyl 1- pyrazolyl,isoxazolyl and 1',2',3'/-triazolylmethoxy-2-methyl-6-nitroindole-3-carboxylate by 1,3-dipolar cycloaddition of diphenylnitrilimine,p-chlorobenzo-nitrile,benzylazide with ethyl l-allyloxy(propargyloxy)-2-methyl-6-nitroindole-3-carboxylate 2i,2j is reported.