Reduction of carbonyl compounds with sodium borohydride in the presence of clays in aprotic solvents

摘要

The selective reduction of carbonyl group of various aromatic and aliphatic compounds bearing different functional groups with sodium borohydride in the presence of clay in aprotic solvents give 72-93% yield of corresponding alcohols.Heterogeneous reactions that are facilitated by clays have received great attention in recent years.Montmorillonite clays have been used in a number of oxidation,reduction and other organic reactions as catalyst and also as solid support for the reagents.