1,3-Dipolar reactions for the synthesis of new substituted isoxazolidines and isoxazoles

摘要

Unsaturated oximes are treated with dipolarophiles like acrylonitrile and methyl acrylate to furnish new 3,4-disubstituted and 3,5-disubstituted isoxazolidines. Reactions of unsaturated oximes with dimehtylacetylene-dicarboxylate yield 3,4-disubstituted isoxazoles.