Novel synthesis and antibacterial activity of 15-iminobenzothiazolo[2,3-b] pyrimido[5,6-e]pyrimido[2,3-b]benzothiazol-14(H)-one and its 3,10-disubstituted derivatives

摘要

Novel heterocyclic compound 15-iminobenzothiazolo[2,3-b]pyrimido[5,6-e]pyrimido[2,3-b] benzothiazol-14(H)-one and its 3,10-disubstituted derivatives 3a-l have been synthesized by the reaction of 2-thiomethyl-3-cyano-8-H/substituted-pyrimido[2,l-b]benzothiazol-4(H)-one la-c with 2-amino-6-H/ substituted benzothiazoles 2a-d.