Synthesis and antimicrobial activities of some imidazole subsittuted indoles

摘要

th ecompounds 1-subsstituted 2-(imidazol-1-yl)-3-(4,5-diarylimidazol-2-yl)indoles 2,1-substituted 2-(imidazol-1-yl)-3-(phenanthro[9,10-d]imidazol-2-yl)indoles 3 and 1-substituted 2-(imidazol-1-yl)-3-(benzimidazol-2-yl)indoles 4 have been synthesized from 1-substituted 2-(imidazol-1-yl)-3-formylindole 1.The structural elucidation of the synthesised compounds has been performed by IR,~1H NMR and mass spectroscopic data and elemetnal analyses.antimicarobial activities of the compouns are examined and notable antifungal activity is obtained from some o the compounds as expected in comparison with the control agent ketoconazole.