Pressure mediated reduction of nitro to amino functionality with FeSO_4/NH_3/H_2O/EtOH system

摘要

Pressure mediated reduction of nitro to amino group by FeSO_4/NH_3/H_2O/EtOH system has been carried out. Moderate nitrogen pressure (1.1 MPa at reaction temperature) at 100 deg C for 4 h has almost doubled the yield to 70.7% from 39.7% when no pressure is applied. Functional groups like chloro and olefinic double bond remain intact but esters are incompatible.