The hereditary transmission of high glutathione transferase activity towardstrans-stilbene oxide in human mononuclear leukocytes

摘要

High glutathione transferase activity towardstrans-stilbene oxide has been observed in resting mononuclear leukocytes only in a portion of the individuals examined. Approximately 46 of a population of 248 individuals demonstrated this high activity. In addition, eight families have been investigated in order to elucidate the hereditary transmission of this activity. The results are consistent with a dominant expression of a single gene located on an autosomal chromosome for this high glutathione transferase activity.