Multivariate Analysis of Hachinski’s Scale for Discriminating Senile Dementia of the Alzheimer’s Type from Multiinfarct Dementia

摘要

The need for an accurate clinical scale to aid in the diagnosis of senile dementia of the Alzheimer’s type (SDAT) is clear in terms of both patient care and research. The ischemic scale of Hachinski, which differentiates multiinfarct dementia from primary degenerative dementia, has been criticized as lacking in validity. This study is a cluster by case analysis of the data from Hachinski’s original report. The multivariate analysis provides support for those clinicopathologic studies that have found Hachinski''s ischemic score of va