Synthesis and characterization of functional superparamagnetic nanocomposites containing γ-Fe_2O_3, dexamethasone sodium phosphate and poly aniline

摘要

Superparamagnetic nanomaterials are showing great prospects in medical treatment with targeted medicine. A conceptually new method has been developed for the synthesis of a superparamagnetic nanocomposite, γ-Fe_2O_3/PANI-DSP (γ-Fe_2O_3/PANI doped with dexamethasone sodium phosphate). The properties of γ-Fe_2O_3/PANI-DSP are tested using FTIR, UV-vis, energy dispersive X-ray, vibrating sample magnetometer, transmission electron microscopy and cyclic voltammetry. The results show that the electric conductivity of γ-Fe_2O_3/PANI-DSP is as high as 0.11 S cm1, while the saturated magnetizations of γ-Fe_2O_3/PANI-DSP (11.3 emu g~(-1)) decreases in comparison with γ-Fe_2O_3/PANI (29.1 emu g~(-1)). The morphology of γ-Fe_2O_3/PANI-DSP appears as spherical particles with a diameter of approximately 50 nm, which indicates that γ-Fe_2O_3/PANI-DSP would be highly favored in the chemotherapy of a variety of cancers.