Analysis of Bone Repair and Inflammatory Process Caused by Simvastatin Combined With PLGA plus HA plus beta TCP Scaffold

Encarnacao Isis Carvalho; Ferreira Xavier Carlos Clessius; Bobinski Franciane; Soares dos Santos Adair Roberto; Correa Marcio; Torres de Freitas Sergio Fernando; Aragonez Aguedo; Goldfeder Eliane Maria; Rodriguez Cordeiro Mabel Mariela

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Analysis of Bone Repair and Inflammatory Process Caused by Simvastatin Combined With PLGA plus HA plus beta TCP Scaffold

机译：辛伐他汀联合PLGA加HA加βTCP支架引起的骨修复和炎症过程分析

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Purpose: This study evaluated the tissue and inflammatory responses to the use of simvastatin and poly(lactic-co-glycolic acid) + hydroxyapatite + beta-tricalcium phosphate (PLGA+HA+beta TCP) scaffold for bone repair.

机译：目的：本研究评估了辛伐他汀和聚乳酸-乙醇酸+羟基磷灰石+β-磷酸三钙（PLGA + HA +βTCP）支架用于骨修复的组织和炎症反应。

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来源
《Implant dentistry 》 |2016年第1期| 共9页
作者
Encarnacao Isis Carvalho; Ferreira Xavier Carlos Clessius; Bobinski Franciane; Soares dos Santos Adair Roberto; Correa Marcio; Torres de Freitas Sergio Fernando; Aragonez Aguedo; Goldfeder Eliane Maria; Rodriguez Cordeiro Mabel Mariela;
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正文语种 eng
中图分类口腔科学 ;
关键词
osteogenesis; bone density; TNF alpha; IL1 beta;

机译：成骨;骨密度;TNFα;IL1β;

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专利

1. Analysis of Bone Repair and Inflammatory Process Caused by Simvastatin Combined With PLGA plus HA plus beta TCP Scaffold [J] . Encarnacao Isis Carvalho, Ferreira Xavier Carlos Clessius, Bobinski Franciane, Implant dentistry . 2016 ,第1期

机译：辛伐他汀联合PLGA加HA加βTCP支架引起的骨修复和炎症过程分析
2. Ridge Preservation After Maxillary Third Molar Extraction Using 30% Porosity PLGA/HA/beta-TCP Scaffolds With and Without Simvastatin: A Pilot Randomized Controlled Clinical Trial [J] . Oliveira Miguel Noronha, Rau Levy Hermes, Marodin Aline, Implant dentistry . 2017 ,第6期

机译：脊柱保存在上颌第三摩尔萃取后使用30％孔隙率PLGA / HA /β-TCP支架，其中没有辛伐他汀：试验随机对照临床试验
3. An osteoconductive PLGA scaffold with bioactive beta-TCP and anti-inflammatory Mg(OH)(2) to improve in vivo bone regeneration [J] . Go Eun Jin, Kang Eun Young, Lee Seul Ki, Biomaterials Science . 2020 ,第3期

机译：具有生物活性β-TCP和抗炎Mg（OH）（2）的骨导电PLGA支架，以改善体内骨再生
4. The PLGA/TCP/Icaritin Composite Scaffolds Recruit Mesenchymal Stem Cells to Bone Defect Region During the Repair Process of Steroids Associated Osteonecrosis [C] . Dong YAO, Xinhui XIE, Xinluan WANG, World biomaterials congress . 2012

机译：PLGA / TCP / Icaritin复合支架在类固醇相关的骨坏死修复过程中将间充质干细胞招募至骨缺损区。
5. Bioactive PLGA/TCP Composite Scaffolds Incorporating Phytomolecule Icaritin Developed for Bone Defect Repair. [D] . Chen, Shihui. 2012

机译：结合植物分子伊卡肽素的生物活性PLGA / TCP复合支架，专为修复骨缺损而开发。
6. Adenovirus-mediated transfer of VEGF into marrow stromal cells combined with PLGA/TCP scaffold increases vascularization and promotes bone repair in vivo [O] . Chunguang Duan, Jian Liu, Zhi Yuan, 2014

机译：腺病毒介导的VEGF与PLGA / TCP支架相结合转移到骨髓基质细胞中可增加血管形成并促进体内骨修复
7. Cytotoxicity analysis of PLGA+HA β TCP scaffolds incorporating simvastatin for bone regeneration [O] . Fernanda Haverroth, Mariane Sordi, Ariadne Da Cruz, 2018

机译：PLGA +HAβTCP支架的细胞毒性分析，掺入辛伐他汀的骨再生

Analysis of Bone Repair and Inflammatory Process Caused by Simvastatin Combined With PLGA plus HA plus beta TCP Scaffold

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