Granzyme A expression by normal rat natural killer (NK) cellsin vivoand by interleukin 2‐activated NK cellsin vitro

摘要

AbstractGranzyme A (TSP‐1) is a serine esterase expressed in cytotoxic T and natural killer (NK) cell lines. Its presence inin vivoprimed T cells is disputed at present. Here we show that normal rat NK cells contain granzyme Ain vivoand that its expression is augmented by their short‐termin vitrotreatment with IL2. Granzyme A expression in a NK cell population with LAK activity has also been exami