Bone Regenerative Efficacy of Limited-Dose Escherichia Coli-Derived rhBMP-2 With Biphasic Calcium Phosphate Carrier in Rabbit Calvarial Defect Model

You Hoon; Yoon So-Ra; Lim Hyun-Chang; Lee Jung-Seok; Jung Ui-Won; Choi Seong-Ho

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Bone Regenerative Efficacy of Limited-Dose Escherichia Coli-Derived rhBMP-2 With Biphasic Calcium Phosphate Carrier in Rabbit Calvarial Defect Model

机译：有限剂量大肠杆菌衍生的rhBMP-2与双相磷酸钙载体在兔颅骨缺损模型中的骨再生功效

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Purpose: The aim of this study was to characterize the healing in rabbit calvarial bone defects after delivery of limited-dose (1.5 mu g) Escherichia coli-derived recombinant human bone morphogenetic protein-2 (ErhBMP-2), and evaluate biphasic calcium phosphate (BCP) as a carrier.

机译：目的：本研究的目的是表征有限剂量（1.5微克）大肠杆菌衍生的重组人骨形态发生蛋白2（ErhBMP-2）递送后兔颅骨骨缺损的愈合，并评估双相磷酸钙（BCP）作为载体。

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《Implant dentistry》 |2016年第1期|共8页
作者
You Hoon; Yoon So-Ra; Lim Hyun-Chang; Lee Jung-Seok; Jung Ui-Won; Choi Seong-Ho;
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正文语种 eng
中图分类口腔科学;
关键词
biphasic calcium phosphate; bone morphogenetic protein 2; bone regeneration; bone substitutes; rabbit calvaria;

机译：双相磷酸钙;骨形态发生蛋白2;骨再生;骨替代物;兔颅盖;

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1. Bone Regenerative Efficacy of Limited-Dose Escherichia Coli-Derived rhBMP-2 With Biphasic Calcium Phosphate Carrier in Rabbit Calvarial Defect Model [J] . You Hoon, Yoon So-Ra, Lim Hyun-Chang, Implant dentistry . 2016,第1期

机译：有限剂量大肠杆菌衍生的rhBMP-2与双相磷酸钙载体在兔颅骨缺损模型中的骨再生功效
2. Bone formation of block and particulated biphasic calcium phosphate lyophilized with Escherichia coli-derived recombinant human bone morphogenetic protein 2 in rat calvarial defects. [J] . Kim JW, Choi KH, Yun JH, Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics . 2011,第3期

机译：在大鼠颅盖缺损中用大肠杆菌衍生的重组人骨形态发生蛋白2冻干的块状和颗粒状双相磷酸钙的骨形成。
3. Volumetric bone regenerative efficacy of biphasic calcium phosphate-collagen composite block loaded with rhBMP-2 in vertical bone augmentation model of a rabbit calvarium [J] . KimJ.-W., JeongI.-H., LeeK.-I., Journal of biomedical materials research, Part A . 2012,第12期

机译：rhBMP-2负载的磷酸钙-胶原双相复合材料块在兔颅骨垂直骨增强模型中的体积骨再生功效
4. New calcium phosphate bioceramic for bone regeneration: a study in rabbit critical-sized calvarial defects. [C] . Fernando Pozzi Semeghini Guastaldi, Edson de Almeida Filho, Elcio Marcantonio Junior, Society for Biomaterials annual meeting and exposition . 2017

机译：用于骨骼再生的新型磷酸钙生物陶瓷：对兔临界大小颅骨缺损的研究。
5. Evaluation of an in situ formed Bioresorbable Membrane and Hyperbaric Oxygen on Bone Regeneration using Alloplastic Bone Substitutes in Critical Sized Rabbit Calvarial Defects. [D] . Humber, Craig Curtis. 2010

机译：使用异体骨替代物治疗严重家兔颅骨缺损，评估原位形成的生物可吸收膜和高压氧对骨再生的影响。
6. Rapid bone regeneration by Escherichia coli-derived recombinant human bone morphogenetic protein-2 loaded on a hydroxyapatite carrier in the rabbit calvarial defect model [O] . Chung-Hoon Chung, You-Kyoung Kim, Jung-Seok Lee, 2015

机译：兔颅盖缺损模型中载于羟基磷灰石载体上的大肠杆菌来源的重组人骨形态发生蛋白-2的快速骨再生
7. Guided bone regeneration using 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC)-cross-linked type-I collagen membrane with biphasic calcium phosphate at rabbit calvarial defects [O] . Jin-Young Park, Im-Hee Jung, You-Kyoung Kim, 2015

机译：使用1-乙基-3-（3-二甲基氨基丙基）碳二亚胺（EDC）交联的I型胶原蛋白膜和双相磷酸钙在兔颅骨缺损处引导骨再生
8. Effect of Calcium Phosphate Coating and rhBMP-2 on Bone Regeneration in Rabbit Calvaria Using Poly(propylene fumarate) Scaffolds. [R] . Dadsetan, M., Guda, T., Runge, M. B., 2015

机译：磷酸钙涂层和rhBmp-2对聚（丙烯酸富马酸酯）支架材料对兔颅骨骨再生的影响。

Bone Regenerative Efficacy of Limited-Dose Escherichia Coli-Derived rhBMP-2 With Biphasic Calcium Phosphate Carrier in Rabbit Calvarial Defect Model

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