Synthese von benzanellierten Carbacephamen, 1. Mitt.

摘要

The direct intramolecular acylation and alkylation of the phenylsulfonylmethyl-group in the β-lactames5aand7are not successful. The postulated intermediate8of the acylating reaction could be quenched with trimethylchlorosilane as the stable silylketale10. Desulfonation and desilylation of10leads to the title compound12. The reaction of7with base does not result in a carbacephame. Instead, the benzob-azepinones15c,dhave been obtained