In Japan, there are at present more than 30 PET (Positron Emission Tomopgraphy) facilities. The movements of medical insurance application to the PET diagnosis using 18{sup left}F FDG (2-18{sup left}F -fluoro-2-deoxy-glucose) by the Ministry of Health and Welfare are being enhanced by PET related people. Therefore, more clinical centers using PET system are expected to be built in the near future. HM12 Cyclotron was developed to meet such market demands for PET, and the prototype machine has been rent to Cyclotron Radio Isotope Center (CYRIC) of Tohoku University since Oct. 1998 for their use of clinical research with positron emitters like 11{sup left}C, 13{sup left}N, 15{sup left}O and 18{sup left}F. We got many technical data of HM12 Cyclotron on the clinical base. The data was enough to establish the reliability of HM12 system operation under the clinical condition. The first commercial product of HM12 Cyclotron was delivered to National Cancer Center in March 2000. The final performance test will be finished by the end of June 2000.
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