Expression of the plasmid pKM101-determined DNA repair system inrecA−andlex−strains ofEscherichia coli

摘要

pKM101, a plasmid R factor of the N compatibility group increases methylmethane sulfonate mutagenesis and diminishes UV-killing inrecA+lex+andrecA+lex−strains, but not inrecA−lex+strains. The induction of a “reclex” dependent colicin is not present inlex−strains carrying the pKM101 factor. These facts indicate that pKM101 acts through an error-prone DNA repair system, which isrecA+dependent, but notlex+