Synthetic Studies on Vitamin D3Analogues: The Synthesis of 8‐P‐(Hydroxymethyl)‐Phenyl‐Des‐A, B‐Cholest‐8( 9) +8( 14)‐ENE

摘要

AbstractThe Grignard reagent derived fromp‐bromobenzyltetrahydropyranyl ether on reaction with the des‐A, B‐cholestan‐8‐one yielded 8‐p‐(terahydropyran‐2′‐yloxymethyl)‐phenyl‐des‐A, B‐cholestan‐8‐ol which on treatment with H2SO4to give 8‐p‐(hydroxymethyl)‐p