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首页> 外文期刊>Immunotherapy >US FDA-approved monoclonal antibody boosts cancer vaccine's efficacy
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US FDA-approved monoclonal antibody boosts cancer vaccine's efficacy

机译:美国FDA批准的单克隆抗体可增强癌症疫苗的功效

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摘要

While cancer vaccines can be successful over a short period, eventually the immune system stops responding and the tumor begins to grow again. Tregs are integral to this reduced response, as they regulate the immune system to reduce its response once an infection has been cleared. Tumors exploit Tregs, which even surround the tumor and prevent tumor-fighting cells from reaching the cancerous cells within.
机译:尽管癌症疫苗可以在短期内获得成功,但最终免疫系统会停止响应,肿瘤开始再次生长。 Treg是这种减少的反应不可或缺的组成部分,因为一旦感染被清除,它们就会调节免疫系统以降低其反应。肿瘤利用Tregs,Tregs甚至围绕着肿瘤,并阻止了抗肿瘤细胞到达其中的癌细胞。

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