Candida albicans' pH regulated antigen 1 (Pra1) preferentially targets and inactivates human complement C3 and C3 activation fragments to evade host immune attack

Dasari Prasad; Luo Shanshan; Reiher Nadine; Hartmann Andrea; Jacksch Susanne; Wende Elisabeth; Barz Dagmar; Beyersdorf Niklas; Huenig Thomas; Klos Andreas; Skerka Christine; Zipfel Peter F.

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Candida albicans' pH regulated antigen 1 (Pra1) preferentially targets and inactivates human complement C3 and C3 activation fragments to evade host immune attack

机译：白色念珠菌的pH调节抗原1（Pra1）优先靶向并灭活人类补体C3和C3激活片段以逃避宿主免疫攻击

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来源
《Immunobiology: Zeitschrift fur Immunitatsforschung》 |2016年第10期|共1页
作者
Dasari Prasad; Luo Shanshan; Reiher Nadine; Hartmann Andrea; Jacksch Susanne; Wende Elisabeth; Barz Dagmar; Beyersdorf Niklas; Huenig Thomas; Klos Andreas; Skerka Christine; Zipfel Peter F.;
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正文语种 eng
中图分类医学免疫学;
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入库时间 2022-08-18 10:24:58

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1. Candida albicans' pH regulated antigen 1 (Pra1) preferentially targets and inactivates human complement C3 and C3 activation fragments to evade host immune attack [J] . Dasari Prasad, Luo Shanshan, Reiher Nadine, Immunobiology: Zeitschrift fur Immunitatsforschung . 2016,第10期

机译：白色念珠菌的pH调节抗原1（Pra1）优先靶向并灭活人类补体C3和C3激活片段以逃避宿主免疫攻击
2. Candida albicans' pH regulated antigen 1 (Pra1) is a protease that inactivates human C3, blocks C3a anti-fungal activity and C3a receptor binding [J] . Dasari Prasad, Luo Shanshan, Reiher Nadine, Molecular Immunology . 2015,第1期

机译：白色念珠菌的pH调节抗原1（Pra1）是一种蛋白酶，可以使人C3失活，阻断C3a的抗真菌活性和C3a受体的结合
3. The pH regulated antigen 1 (Pra1) of Candida albicans cleaves the human complement component C3 and blocks C3a mediated anti-fungal activity and effector function. [J] . Dasari P., Luo S., Reiher N., Mycoses: Diagnosis, therapy and prophylaxis of fungal diseases . 2015,第Suppla3期

机译：白色念珠菌的pH调节抗原1（Pra1）裂解人补体成分C3，并阻断C3a介导的抗真菌活性和效应子功能。
4. Growth inhibition of candida albicans by interleurkin-2-activated human peripheral blood mononuclear cells [C] . Li Wengong, Chen Yinlin, Zhou Liyi, Proceedings of the Fourth China-Jpan international congress of mycology . 1998

机译：白介素2激活的人外周血单个核细胞对白色念珠菌的生长抑制
5. Generation of Multiple Fluid-Phase C3b:Plasma Protein Complexes During Complement Activation. Functional Significance and Possible Implications in C3 Glomerulopathies. [D] . Ramadass, Mahalakshmi. 2013

机译：补体激活过程中多个液相C3b：血浆蛋白复合物的产生。 C3肾小球病变的功能意义和可能意义。
6. The classical and alternative pathways of complement activation play distinct roles in spontaneous C3 fragment deposition and membrane attack complex (MAC) formation on human B lymphocytes [O] . Robert Graham Quinton Leslie, Claus Henrik Nielsen 2004

机译：补体激活的经典途径和替代途径在人B淋巴细胞上自发性C3片段沉积和膜攻击复合物（MAC）形成中起不同作用
7. The classical and alternative pathways of complement activation play distinct roles in spontaneous C3 fragment deposition and membrane attack complex (MAC) formation on human B lymphocytes [O] . Leslie Robert Graham Quinton, Nielsen Claus Henrik 100

机译：补体激活的经典途径和替代途径在人B淋巴细胞上自发性C3片段沉积和膜攻击复合物（MAC）形成中起不同作用

Candida albicans' pH regulated antigen 1 (Pra1) preferentially targets and inactivates human complement C3 and C3 activation fragments to evade host immune attack

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