Deceased donor kidneys allocated out of sequence by organ procurement organizations

摘要

Deceased donor kidney allocation follows a ranked match‐run of potential recipients. Organ procurement organizations (OPOs) are permitted to deviate from the mandated match‐run in exceptional circumstances. Using match‐run data for all deceased donor kidney transplants (Ktx) in the US between 2015 and 2019, we identified 1544?kidneys transplanted from 933 donors with an OPO‐initiated allocation exception. Most OPOs (55/58) used this process at least once, but 3 OPOs performed 64 of the exceptions and just 2 transplant centers received 25 of allocation exception Ktx. At 2 of 3 outlier OPOs these transplants increased 136 and 141 between 2015 and 2019 compared to only a 35 increase in all Ktx. Allocation exception donors had less favorable characteristics (median KDPI 70, 41 with history of hypertension), but only 29 had KDPI?≥?85 and the majority did not meet the traditional threshold for marginal kidneys. Allocation exception kidneys went to larger centers with higher offer acceptance ratios and to recipients with 2 fewer priority points—equivalent to 2?less years of waiting time. OPO‐initiated exceptions for kidney allocation are growing increasingly frequent and more concentrated at a few outlier centers. Increasing pressure to improve organ utilization risks increasing out‐of‐sequence allocations, potentially exacerbating disparities in access to transplantation.