Bacterial Chemotaxis: The Early Years of Molecular Studies

摘要

This review focuses on the early years of molecular studies of bacterial chemotaxis and motility, beginning in the 1960s with Julius Adler’s pioneering work. It describes key observations that established the eld and made bacterial chemotaxis a paradigm for the molecular understanding of biological signaling. Consideration of those early years includes aspects of science seldom described in journals: the accidental ndings, personal interactions, and scientic culture that often drive scientic progress.