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机译:Counterintuitive structural and functional effects due to naturally occurring mutations targeting the active site of the disease-associated NQO1 enzyme
Univ Granada;
Acad Sci Czech Republ;
Univ La Laguna;
catalytic mechanism; genotype-phenotype correlations; protein structure-function; structural stability; MASS-SPECTROMETRY; SIDE-CHAINS; BINDING; PATHOGENICITY; CONSEQUENCES; PREDICTIONS; VARIANTS; EXCHANGE; DATABASE; NAD(P)H;