The selection of an internal or external pinch valve for applications such as analytical chemistry, diagnostics, medical equipment or next-generation sequencing, must be carefully examined. In general, internal pinch valves are the best choice when low internal volume, low carryover volume and long life are important factors. External pinch valves are a great solution for applications where easy tubing replacement is a desirable attribute. Both valve types offer clean flow paths, relatively low internal volumes (as compared to other types of valves), and excellent compatibility with fluids commonly used in the medical and scientific industries.
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