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Multiple myeloma or metastatic carcinoma breast: Diagnostic dilemma in a case presenting with lytic bony lesion

机译:多发性骨髓瘤或转移性乳腺癌:存在溶解性骨病变的诊断难题

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摘要

Carcinoma breast is common tumor which tends to metastasize to different organs but diagnostic difficulty may arise if known case of carcinoma eventually presents with another secondary malignancy with clinical features which closely mimics with metastatic carcinoma. This overlapping of symptoms may lead to delayed diagnosis of secondary malignancy with worsening of the condition of patient due to lack of specific treatment. The present case is being reported where a known case of primary breast carcinoma presented with scapular erosions suggesting metastasis. However, despite treatment her worsening condition necessitated further work up revealing multiple myeloma. The case signifies the pitfall due to overlapping of symptoms and draws attention to the fact that every known case of primary carcinoma suggestive of metastasis should also be investigated in light of another secondary malignancy. Early diagnosis of secondary malignancy followed by specific treatment would be helpful in improved prognosis of the patient.
机译:乳腺癌是常见的肿瘤,倾向于转移到不同的器官,但是如果已知的癌症病例最终出现另一种具有与转移癌密切相似的临床特征的继发性恶性肿瘤,则可能会出现诊断困难。症状的这种重叠可能导致继发性恶性肿瘤的诊断延迟,并且由于缺乏特异性治疗而使患者的病情恶化。据报道本病例,其中已知的原发性乳腺癌病例出现肩骨糜烂提示转移。然而,尽管接受了治疗,但她的病情恶化仍需要进一步检查以发现多发性骨髓瘤。该病例表明由于症状重叠而导致的陷阱,并提请注意以下事实:每个已知的提示转移的原发癌病例也应根据另一个继发性恶性肿瘤进行研究。继发恶性肿瘤的早期诊断,然后进行具体治疗,将有助于改善患者的预后。

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