Radiotherapy is a local therapy modality and is integrated in a multimodal treatment concept. It is mandatory and standard in all patients with breast-preserving therapy and is also indicated in the majority of patients who undergo mastectomy. Adjuvant radiotherapy generally improves local tumor control and reduces the risk of a locoregional recurrence by a factor of 3-4 [1-3]. In patients with a high risk of local recurrence, improved local control is associated with improved survival [1, 3-8]. Antineoplastic adjuvant systemic therapy may contribute to local control and enhances the efficacy of radiotherapy but its effect alone is not sufficient to replace radiotherapy [1, 3, 9].
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