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外文期刊>Bulletin of the Korean Chemical Society
>Facile one-pot three-component route to an assembly of 2-amino-4H-chromenes and spirochromenes promoted via ceria nanoparticles in a benign manner
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Facile one-pot three-component route to an assembly of 2-amino-4H-chromenes and spirochromenes promoted via ceria nanoparticles in a benign manner
In this study,a series of 2-amino-4H-chromenes and spirochromenes were elaborated and synthesized via a new sustainable one-pot three-component strategy from easily available materials including phloroglucinol,malononitrile,and aldehydes/isatins.Ceria nanoparticles(CeO2 NPs)were successfully applied as an effective catalyst that recycled and reused with a marginal decrement in its catalytic performance.The Lewis acid-base nature of the described nanocatalyst afforded the high yields of target products.The reaction is run in ethanol as a green solvent to create an environment-friendly process.The other salient merits of this methodology are a broad substrate scope,a simple operation,shorter reaction times,and no need for column chromatographic purification.
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