Revalue associations of short-term exposure to air pollution with respiratory hospital admissions in Lanzhou, China after the control and treatment of current pollution

摘要

Significant progress has been made in air pollution control Lanzhou, China recently, however, there was only onestudy so far on the assessment on health gains from air quality improvement after adopting strict air pollutioncontrol measures. The present study aimed to estimate the short-term effects of six criteria air pollutantsincluding PM_(2.5), PM_(10), NO_2, SO_2, CO and O_3 on respiratory admissions in Lanzhou, China, then compare theresults of our study with those earlier studies conducted in Lanzhou before the implementation of air pollutioncontrol measures. Data on daily hospital admissions from the three largest hospitals in Lanzhou and daily airpollution concentration and meteorological variable were collected during a 4-year period (2014–2017). Ageneralized additive model; adjusted for long-term trend, seasonality, and other potential confounders was doneto quantitatively assess the influences of air pollutants on daily respiratory admissions and analyze the influencesof different seasons, sexes, and age groups. The most apparent effects for PM_(2.5), PM_(10), SO_2, CO and O_3 on respiratoryhospitalizations were observed at lag6, and lag7, respectively, and a 10μg/m3 increase in PM_(2.5), PM_(10),SO_2, CO and O_3 concentration were associated with 0.885 (95CI: 0.414～1.358), 0.328 (95CI: 0.145～0.511), 3.005 (95CI: 1.689～4.339), 3.199 (95CI: 0.912～5.537) for CO, 0.733 (95Cl:0.263～1.205) increase in respiratory admission, respectively. No remarkable association was found betweenNO_2 and respiratory disease hospitalisation. Females and younger groups were more susceptible to air pollutantthan males and elderly groups. Together, we demonstrated that the positive associations were more pronouncedin the cold season than in the warm season. The findings in present study suggest that even in Lanzhou, where airquality has been improved dramatically, positive associations still exist between air pollution and daily numberof total respiratory admission.