A comparison of homogeneous and heterogeneous copper catalyzed arylation of amines

摘要

Comparison of the homogeneous and heterogeneous copper-catalyzed arylation of model primary amines with (hetero)-aryl iodides in DMSO revealed a comparable efficiency of CuI and commercially available unsupported copper nanoparticles (25 nm size) in the presence of 2-isohutyryl-cyclohexanone or L-proline.