SURGICAL OUTCOMES OF VASOPROLIFERATIVE RETINAL TUMORS' REFRACTORY TO NONINVASIVE THERAPIES

摘要

Purpose: To evaluate the outcomes of surgical treatment of refractory vasoproliferative retinal tumors (VPTs) and its complications. Methods: Clinical charts of all patients diagnosed with VPTs who underwent surgical treatment from 2005 to 2020 were reviewed. Clinical features, surgical techniques, and outcomes were evaluated. Results: From 25 eyes of 23 patients with VPTs, 17 (68) eyes underwent surgical intervention to treat tumor activity and associated complications including epiretinal membrane (n = 10, 59), retinal detachment (n = 8, 47), and vitreous hemorrhage (n = 3, 18). All eyes underwent pars plana vitrectomy with endolaser/cryotherapy to control tumor activity and to treat associated complications. Three cases required tumor resection. At the end of follow-up (mean 55.4 months, range 2-305 months), no eye presented tumor activity or retinal detachment after one or two surgeries. There was no epiretinal membrane recurrence. The mean baseline best-corrected visual acuity was 1.2 +/- 0.7 logMAR, and the mean final best-corrected visual acuity was 0.7 +/- 0.6 logMAR (P < 0.05). The best-corrected visual acuity improved two or more lines in 12 (70.5) eyes at the end of follow-up. Conclusion: In this series of patients with large active VPTs, surgical intervention allowed control of the tumor activity in all patients and provided overall satisfactory anatomic and functional outcomes.