A new lactam, 5-hydroxy-1-(4-hydroxyphenyl)methyl-2-pyrrolidinone (1), was isolated from the ethyl acetate extract of Cannabis sativa L. The structure was established by spectroscopic analyses, including 1D and 2D NMR (1H, 13C, COSY, HMBC, HSQC) and EI-MS, and comparison with the data of known analogs.
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